THC, the main psychoactive compound in cannabis, exists in various forms like Delta-9, Delta-8, and Delta-10, each offering distinct effects and potential benefits. Delta-9 THC is most common, known for strong psychoactive properties, while Delta-8 and Delta-10 provide milder experiences. Non-psychoactive variants such as THCA and THCV offer health benefits without the high, and newer forms like THCP and THC-O are being explored for their unique effects. Understanding these differences is key to tailoring your cannabis experience to your specific needs and preferences. Always ensure you're informed about the type and source of THC in your products for the safest and most beneficial use.
You may have already heard of THC (tetrahydrocannabinol), a psychoactive compound found in the cannabis plant. With over 400 different compounds found in cannabis and all the different types of THC, tetrahydrocannabinol and its interaction with other cannabinoids are more complex than you may think.
The cannabis plant has a long history of being not only a recreational substance but also a traditional medicine in various cultures. As we learn more about the plant, its therapeutic effects are gradually transpiring. Because of the increasing number of research initiatives, we discover more about the cannabis plant with every passing year.
Several studies indicate that THC can provide relief from chronic pain and aid in a range of medical conditions. So, what is THC? How does it work? And, how many types of THC are there?
Let's dive deeper into the most commonly found THC types, the lesser-known ones, and also discuss their individual benefits.
THC or tetrahydrocannabinol is a cannabinoid - a group of compounds found in the cannabis plant. There are over 100 cannabinoids known this far, some better studied than others. THC is one of the most well-known cannabinoids in cannabis, with the other one being CBD (or cannabidiol).
The most prominent psychoactive effects of THC are alterations in mood, alertness, and cognitive functions. However, in addition to its effect on the mental state, there are types of THC that also have potential medical effects.
A fact that is often overlooked is that THC is not a specific compound with the same genetic attributes. Instead, there are several variations of THC called chemical analogs, which distinguish them from each other. All these variations somewhat have different properties and medical benefits.
If you have only started exploring the world of natural plant healing and are curious to know about the different options available, read on to discover the different types of THC and their potential health benefits.
Delta-9 THC, is what everybody usually talks about when talking about THC, this is the most abundantly found variation of THC in the cannabis plant. This compound is found in both male and female cannabis plants but exists in high concentrations, mainly in female plants.
Delta-9 THC binds to the CB1 receptors in the brain and nervous system in order to produce mind-altering effects such as feelings of mental and physical disassociation from time, reduced memory, and bodily relaxation.[Source]
Despite being a psychoactive substance, Delta-9 THC is used for various treatments. Some of the observed health benefits of the Delta-9 THC. Some of these include
- Promotes sleep
- Helps ease mood disorders, anxiety, andPTSD
- Relieves migraine-related orchronic pain
- Decreases the feeling ofnausea or vomiting
- Antibacterial and antioxidant effects
- Dealing with lowappetite
- Helps treat inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS)
Delta-8 formulates when Delta-9 ages and gets exposed to oxidation and accounts for less than 1% of the plant, which makes it difficult to yield. In addition, delta-8 is a double bond isomer of Delta-9, which means that they have the same number of elements and atoms but are structurally distinct, and their elements are differently arranged.
Some studies have shown that its consumption results in a more clear-headed and energetic effect. Nevertheless, Delta-8-THC is still considered to have similar psychoactive effects as Delta-9-THC by FDA.[Source]
Delta-8 THCcommunicates with CB1 and CB2 cannabinoid receptors and appears to have several benefits for the body.
However, since delta-8 THC occurs only in small amounts in cannabis, most commercially available delta-8 products are made by chemically converting delta-9 THC or cannabidiol (CBD).
Despite being considered less potent, there are still risks associated with using delta-8 products because of limited research. Although delta-8 THC is federally legal, it is important to note that delta-8 products have not been evaluated by FDA for safe use.
Delta-10 THC is an isomer of the cannabinoid THC that possesses the same chemical properties but is arranged differently, which stimulates different effects. Delta-10 THC appears in extremely low traces, unlike the delta-9 cannabinoid, making it impossible to consume high amounts directly from the plant.
That is why most delta-10 products are developed in labs or synthetically. Both delta-8 and delta-10 are minor cannabinoids, separated by only a few bonds of atoms.
So far, little research has been conducted on the effect of delta-10 on the body.
THCA is usually found in the stems, leaves, and flowers of the cannabis plant, while surprisingly, it is a type of THC that does not have any mind-altering effects.
THCA does not produce the psychoactive effects of THC, which come into effect as molecules attach to CB1 receptors in the nervous system. This is because THCA's structure is not molded for these receptors.
Rather, THCA serves as a source for three other types of THC (THCV, Delta-8 THC, and Delta-9 THC), a process that is stimulated by applying heat. Heating THCA molecules cause the chemical composition and form to change and are hence appropriate to fit into the body's CB1 receptors.
Like other types of THC, THCA also has therapeutic functions of its own. Several studies show that THCA can help treat the following conditions:
THCV is a byproduct of THCA breakdown, formed due to a process called decarboxylation when medical cannabis is dried and vaporized. Although it is gaining popularity for a wide range of positive effects, it is the least known type of THC.
Studies suggest that THCV does not produce mind-altering effects in low doses due to its shorter chain of molecules and lower interactivity with the receptors. However, higher doses give a clear and stimulating high.
This cannabinoid interacts with the CB1 receptors and gives short-lived effects compared to other THC types. One peculiar property of THCV is that it does not stimulate the appetite but acts as an appetite suppressant. Studies show that THCV may offer benefits like:
THCP or tetrahydrocannabiphorol is the most recent cannabinoid to receive attention. This unique analog of THC is said to have 33 times the binding affinity for the CB1 receptors as compared to delta-9 THC, which causes an intense and euphoric effect.
The ability of a compound to bind with the receptors depends on the size of the side chains. THCP is structurally similar to delta-9 THC but has a seven-link side chain. Previously, no other cannabis compound has been found to naturally have more than five-link chains.
For now, THCP lies in the legal grey area, just like delta-8 and delta-10 THC. There is still a substantial amount of research required to find the potential benefits of THCP.
THC-O, also called THC-O acetate, is a hemp-derived synthetic cannabinoid. THC-O's main appeal is that it is synthesized from federally legal hemp, unlike THC which is legalized on a state level only in several states. Nevertheless, the process of making THC-O-acetate includes a highly flammable chemical called acetic anhydride. And just like THCP or Delta-10 THC, THC-O is one of the least researched analogs of THC, which means the potential benefits or side effects are yet to be discovered.
- Rythm Full Spectrum Disposable Vape Pen – Baklava 85.35% THC: Rythm's Baklava vape pen combines convenience with potency, featuring an 85.35% THC content derived from a Kosher Kush x Gelato 41 cross. This Sativa Dominant, full-spectrum oil vape offers an uplifting experience transitioning smoothly into full-body relaxation. Its flavors—a blend of sweet vanilla and distinct tar—are as compelling as its effects.
- Incredibles Gummies Sour Cherry Tart – 100mg THC: Incredibles brings you the essence of cherry in their Sour Cherry Tart Gummies, with a total THC content of 100mg per package. Each gummy ensures a consistent dose of 10mg THC, crafted for precision with pure THC distillate. These gummies strike the perfect balance between the tangy and the sweet, embodying the spirit of indulgence.
- Rythm Flower Animal Face 31.19%: Rythm’s Animal Face flower is an Indica with a THC potency of 35.72%, offering a profile of sweet mint, nuts, pine, and diesel. This strain promises an earthy yet sweet aroma with effects that are both euphoric and relaxing, making it ideal for those seeking relief and bliss.
- Dogwalkers 5 Pack Mini Dogs White Durban 22.74% THC, THCA 24.75%: Dogwalkers' White Durban Mini Dogs pack a sativa-leaning punch in a convenient, portable tin. Each pack contains five .35g pre-rolls with a blend emphasizing clarity and energy, backed by a commitment to supporting animal shelters.
- Dr. Solomon’s Tincture 1:1 Restore 100mg CBD: Dr. Solomon's 1:1 Restore Tincture offers a balanced blend of 100mg CBD and THC, tailored for those seeking both relief and equilibrium. It’s an easy-to-dose solution aimed at diminishing discomfort and revitalizing your steps. This non-habit-forming tincture stands out for its commitment to full-body wellness.
- Beboe Gummies 1:2 Remedy Golden Peach 200mg CBD 100mg THC: Beboe's Golden Peach Gummies are a crafted blend of relaxation and balance, featuring a 1:2 ratio of THC to CBD. With 10mg CBD and 5mg THC per gummy, this 20-pack promises a total of 200mg CBD and 100mg THC. They're designed for a gentle, yet effective, experience with a delightful peach flavor that echoes the product's natural composition.
In our vibrant cannabis community, the blossoming presence of Delta-9 and Delta-8 THC products adds a whole new layer of excitement and options for enthusiasts like us. As these cannabinoids find their way into the hearts (and carts) of people everywhere, we want to share a piece of wisdom that’s as golden as the strains we cherish: the importance of knowing where your cannabis comes from.
Here’s the straight talk—navigating the ever-expanding cannabis universe is thrilling, but it's also crucial to ensure that every purchase is as safe as it is satisfying. That’s where we, at RISE, step in. It's not just about steering clear of the murky waters of the unregulated market; it’s about diving into an ocean of clarity, quality, and trust.
Every item on our shelves is there because it meets high standards of testing, transparency, and compliance. It's our promise to you—a promise of purity, potency, and integrity.
People use cannabis for a variety of reasons; some of the most common conditions are chronic pain, insomnia, and stress.
For the optimal effect, it is necessary to go with the right kind. Choosing from the many cannabis products available online or in dispensaries may be overwhelming. That is why, at RISE dispensaries, we are dedicated to helping you with what best fits your needs.
Every person is different, so you can start by speaking to your doctor, a pharmacist, or a patient care specialist at a nearby RISE Dispensary. Here are products that reviewers said helped them “get some sleep”
Each product is unique. Edibles purchased at RISE Dispensaries are lab-tested and contain the types of THC naturally found in the cannabis plant. The most abundant naturally-occurring type of THC is Delta-9 THC.
Do you have any other questions or are you interested in learning more? Find a RISE Dispensary that’s closest to you.
- Pollio A. The Name of Cannabis: A Short Guide for Nonbotanists. Cannabis Cannabinoid Res. 2016;1(1):234-238. Published 2016 Oct 1. doi:10.1089/can.2016.0027
- The Genetic Structure of Marijuana and Hemp by Jason Sawler, Jake M. Stout, Kyle M. Gardner, Darryl Hudson, John Vidmar, Laura Butler, Jonathan E. Page, Sean Myles
- Watts G. Cannabis confusions. BMJ. 2006;332(7534):175-176. doi:10.1136/bmj.332.7534.175
- Piomelli D, Russo EB. The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD. Cannabis Cannabinoid Res. 2016;1(1):44-46. Published 2016 Jan 1. doi:10.1089/can.2015.29003.ebr
- Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-1364. doi:10.1111/j.1476-5381.2011.01238.x
- UCLA Cannabis Research Initiative
- Lu HC, Mackie K. An Introduction to the Endogenous Cannabinoid System. Biol Psychiatry. 2016;79(7):516-525. doi:10.1016/j.biopsych.2015.07.028
- Δ9-Tetrahydrocannabivarin (THCV): a commentary on potential therapeutic benefit for the management of obesity and diabetes, Journal of Cannabis Research, 2020, Kunle Sanyaolu, Risha Patidar, Adekunle Sanyaolu
- McPartland J.M. (2017) Cannabis sativa and Cannabis indica versus “Sativa” and “Indica”. In: Chandra S., Lata H., ElSohly M. (eds) Cannabis sativa L. – Botany and Biotechnology. Springer, Cham. https://doi.org/10.1007/978-3-319-54564-6_4
- Crean RD, Crane NA, Mason BJ. An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. J Addict Med. 2011;5(1):1-8. doi:10.1097/ADM.0b013e31820c23fa
- Federica Pellati, Vittoria Borgonetti, Virginia Brighenti, Marco Biagi, Stefania Benvenuti, Lorenzo Corsi, “Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer”, BioMed Research International, vol. 2018, Article ID 1691428, 15 pages, 2018. https://doi.org/10.1155/2018/1691428
- A Review on Cannabis sativa: Its Compounds and Their Effects, Ranju Rajput, *Dr. Krishan Kumar Department of Food and Biotechnology, Jayoti Vidyapeeth Women’s University, Jaipur, Rajasthan, India.
Medical marijuana is intended for use by authorized patients only. Marijuana has not been analyzed or approved by FDA and there is limited information on side effects. There may be health risks associated with using marijuana. Scientific research has not yet established the safety of the use of marijuana by women who are pregnant or breastfeeding. Keep marijuana away from children. When under the influence of marijuana, driving is prohibited by law and machinery should not be operated. Registered qualifying patients may not distribute marijuana to any other individual.